Rheumatologist , the Dr. Paul R. Esserman Professor of Medicine at 秘密研究所 Langone, says his team鈥檚 latest study links diminished levels of adenosine, a chemical at the heart of human cellular function, to osteoarthritis (OA), the commonplace, 鈥渨ear-and-tear鈥 form of arthritis. 聽
Dr. Cronstein, who also serves as director of the and chief of the at 秘密研究所 Langone, describes how images from a dozen male research mice, survivors of Superstorm Sandy who had also stopped mating and eating, helped them find a new treatment approach for the common joint disease.
Dr. Bruce Cronstein, the Dr. Paul R. Esserman Professor of Medicine at 秘密研究所 Langone.
Photo: 秘密研究所 Langone Staff
鈥淭hese results support the hypothesis that maintaining extracellular adenosine levels is an important homeostatic mechanism, loss of which contributes to the development of OA,鈥 Dr. Cronstein tells the San Diego Union-Tribune. 鈥淭argeting adenosine A2A receptors might treat or prevent OA.鈥
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