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News from ������� Langone Health

Longest Pig Organ Transplant Survivor Passes 60 Days With New Kidney. (HealthDay)

(1/27) Towana Looney, a 53-year-old woman from Alabama, became the longest-living recipient of a gene-edited pig kidney transplant, having surpassed 60 days since the surgery performed at ������� Langone Health on November 25, with the kidney functioning normally according to Robert Montgomery, MD, DPhil, the H. Leon Pachter, MD, Professor of Surgery, chair, Department of Surgery, ������� Langone Transplant Institute.

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The Targeted Pulse: Recent Approvals In Breast And Colorectal Cancers And The Controversy Over Adjuvant CDK4/6 Inhibitors In Breast Cancer. (Targeted Oncology)

(1/27) Discussing the FDA’s approval of datopotamab deruxtecan “for treating unresectable or metastatic hormone receptor-positive (HR+), HER2-negative (HER2–) breast cancer that has been previously treated with systemic therapy,” Joshua K. Sabari, MD, assistant professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, said, “Rash is a major issue with this therapy, and it is one of the more chronic toxicities. Both therapies [are probably responsible]; they both have EGFR inhibition, but amivantamab likely has more EGFR wild-type inhibition than lazertinib. Lazertinib was more EGFR mutant-specific. In my own experience, they complement each other, but I think most of the effect is driven by amivantamab.”

������� Langone Health Discusses Improving Gut Health. (ABC)

(1/27) On Live with Kelly and Mark, Roshini Raj, MD, clinical associate professor, Department of Medicine, Division of Gastroenterology and Hepatology, discussed improving gut health for better aging during a segment on gut microbiome, highlighting the importance of probiotics, prebiotics, exercise, and stress management.

‘Vicious Cycle’: Are There Benefits To ‘Yo-Yo Dieting?’ (Medscape)

(1/27)* In discussing weight regain, Michael A. Weintraub, MD, clinical assistant professor, Department of Medicine, Division of Endocrinology, Diabetes, & Metabolism, explained that weight loss through lifestyle changes and bariatric surgery is often unsustainable, noting that “we burn less energy” once “our basal metabolic rate decreases,” pushing back “against the weight loss we attain with lifestyle modifications.”

Researchers Work On $56 Million Initiative For Vision Restoration. (Washington Square (NY) News)

The (1/27) More than 40 researchers nationwide are collaborating with �����о��� Langone Health and the �����о��� Grossman School of Medicine on a $56 million project, funded by the Advanced Research Projects Agency for Health, to achieve successful whole-eye transplants over six years, with Shane A. Liddelow, PhD, associate professor, Departments of Neuroscience and Physiology, and Ophthalmology, saying, “The incredibly audacious goal is for us to be able to restore vision in people who have lost their sight.”

Seasonal Suffering: How The Changing Of Seasons Impacts Migraine Patterns. (Weather Channel)

(1/27) Discussing the impact of changing seasons on patients with migraine, Robert H. Fryer, MD, PhD, clinical professor, Department of Neurology, said, “I see many patients where it is the change in seasons, particularly the beginning of the fall season, where their headaches can get much worse.”

We Are In A Mental Health Crisis. A ‘Moonshot’ Is Needed. (Newsday (NY))

(1/27) Kara G. Margolis, MD, clinical associate professor, Department of Pediatrics, writes about the need for a mental healthcare “moonshot.”

Compassion Fatigue: How Oncologists Can Recognize The Signs. (Medscape)

(1/28)* Discussing the impact of compassion fatigue on healthcare workers, Marra G. Ackerman, MD, clinical associate professor, Department of Psychiatry, said that the issue is “a form of coping more than anything.”